Tuning the Drug Loading and Release of DNA-Assembled Gold-Nanorod Superstructures.

Raeesi, Vahid; Chou, Leo Y T; Chan, Warren C W · Adv Mater · 2016

basic_science · Level V

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Abstract

The use of DNA to assemble inorganic nanoparticles into superstructures is an emerging strategy to build non-toxic delivery vehicles for targeting diseases in the body. The impact of the core-satellite nanosystem design in mediating drug storage, drug release (via heat), and killing of HeLa cells in culture is investigated.

Medical subject headings