Assessment of a rapid liquid-based cytology method for measuring sputum cell counts.

Martin, M J; Lee, H; Meakin, G; Green, A; Simms, R L; Reynolds, C; Winters, S; Shaw, D E et al. · Thorax · 2016

other · Level V

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Abstract

Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained using LBC were a strong predictor of sputum eosinophilia (≥3%) determined by the standard method suggesting LBC could be used in the management of asthma.

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