Thrombotic thrombocytopenic purpura: The role of ADAMTS13.
Where this comes from
- Record sourced from PubMed, PMID 27505881.
- Also identified by DOI 10.3949/ccjm.83a.15009.
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Abstract
Thrombotic thrombocytopenic purpura (TTP) is an uncommon, life-threatening disease requiring prompt diagnosis and initiation of therapeutic plasma exchange to improve patient survival. However, diagnosis is often difficult because of atypical presentations and signs and symptoms that resemble other conditions. Measurements of ADAMTS13 activity, ADAMTS13 inhibitor, and ADAMTS13 autoantibody are useful for diagnosing TTP, guiding therapy, and predicting relapse.
Medical subject headings
- ADAMTS13 Protein
- Purpura, Thrombotic Thrombocytopenic