Guidelines to PET measurements of the target occupancy in the brain for drug development.
Level V
Where this comes from
- Record sourced from PubMed, PMID 27514528.
- Also identified by PMC identifier 5047931.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
This guideline summarizes the current view of the European Association of Nuclear Medicine Drug Development Committee. The purpose of this guideline is to guarantee a high standard of PET studies that are aimed at measuring target occupancy in the brain within the framework of development programs of drugs that act within the central nervous system (CNS drugs). This guideline is intended to present information specifically adapted to European practice. The information provided should be applied within the context of local conditions and regulations.
Medical subject headings
- Brain
- Central Nervous System Agents
- Molecular Imaging
- Nerve Tissue Proteins
- Positron-Emission Tomography
- Practice Guidelines as Topic