Bile Acid Analog Intercepts Liver Fibrosis.
Where this comes from
- Record sourced from PubMed, PMID 27518554.
- Also identified by DOI 10.1016/j.cell.2016.08.001.
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Abstract
Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FXR, is effective in treating primary biliary cholangitis, an autoimmune liver disease. It works in patients who fail to respond to or cannot tolerate conventional treatment with the natural bile acid ursodeoxycholic acid (UDCA).