IL-33, Imprimatur of Adipocyte Thermogenesis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27518556.
- Also identified by DOI 10.1016/j.cell.2016.07.051.
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Abstract
Chawla and colleagues find that interleukin-33 is a critical controller of brown and beige adipocyte thermogenesis. Its primary impact is on the splicing of transcripts encoding uncoupling protein-1, resulting in uncoupled respiration and effective heat generation. Interleukin-33 acts perinatally to ensure adaptive thermogenesis lifelong.
Medical subject headings
- Adipose Tissue, Brown
- Interleukin-33