Kidney Macrophages: Unique Position Solves a Complex Problem.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27518559.
- Also identified by DOI 10.1016/j.cell.2016.07.047.
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Abstract
Immune complex-mediated diseases, such as systemic lupus erythematosus, commonly affect the kidney and determine disease prognosis. Stamatiades et al. now propose a kidney-specific mechanism for trans-endothelial transport of small immune complexes that activate strategically positioned tissue resident macrophages.
Medical subject headings
- Kidney
- Lupus Erythematosus, Systemic