Hierarchically Staggered Nanostructure of Mineralized Collagen as a Bone-Grafting Scaffold.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27530607.
- Also identified by DOI 10.1002/adma.201602628.
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Abstract
A hierarchical, intrafibrillarly mineralized collagen (HIMC) is achieved through a selective mineralization progress in the collagenous gap regions mediated by poly(acrylic acid) with appropriate molecular weight. The associated topographical features directly correlate with nanomechanical heterogeneities of the HIMC to accommodate a broad range of external loads. Moreover, this hierarchically staggered nanostructure provides an optimized microenvironment to improve bone regeneration by instructing host cells.
Medical subject headings
- Nanostructures