Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27545588.
- Also identified by DOI 10.1002/adma.201603006.
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Abstract
Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF.
Medical subject headings
- Metal-Organic Frameworks