Integrating genomic information with protein sequence and 3D atomic level structure at the RCSB protein data bank.
Where this comes from
- Record sourced from PubMed, PMID 27551105.
- Also identified by DOI 10.1093/bioinformatics/btw547 and PMC identifier 5167066.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The Protein Data Bank (PDB) now contains more than 120,000 three-dimensional (3D) structures of biological macromolecules. To allow an interpretation of how PDB data relates to other publicly available annotations, we developed a novel data integration platform that maps 3D structural information across various datasets. This integration bridges from the human genome across protein sequence to 3D structure space. We developed novel software solutions for data management and visualization, while incorporating new libraries for web-based visualization using SVG graphics. The new views are available from http://www.rcsb.org and software is available from https://github.com/rcsb/. andreas.prlic@rcsb.orgSupplementary information: Supplementary data are available at Bioinformatics online.
Medical subject headings
- Computational Biology
- Databases, Protein
- Protein Conformation
- Software