Transmission of Drug-Resistant Leprosy in Guinea-Conakry Detected Using Molecular Epidemiological Approaches.
case_series · Level IV
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Abstract
Molecular drug susceptibility testing was performed on skin biopsies from 24 leprosy patients from Guinea-Conakry for the first time. We identified primary drug resistance in 4 cases and a dapsone-resistant cluster caused by the same strain. Primary transmission of drug-resistant Mycobacterium leprae, including a rifampicin-resistant strain, is reported.
Medical subject headings
- Antibiotics, Antitubercular
- Antitubercular Agents
- Drug Resistance, Microbial
- Leprosy
- Mycobacterium leprae