Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu<sub>2-</sub><sub>x</sub> Se Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer.

Zhang, Shaohua; Sun, Caixia; Zeng, Jianfeng; Sun, Qiao; Wang, Guanglin; Wang, Yong; Wu, Yan; Dou, Shixue et al. · Adv Mater · 2016

basic_science · Level V

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Abstract

Ultrasmall PEGylated Cu<sub>2-</sub><sub>x</sub> Se nanoparticles with strong near-infrared absorption have been prepared by an ambient aqueous method. The resultant water-soluble and biocompatible nanoparticles are demonstrated to be a novel nanotheranostic agent for effective deep-tissue photoacoustic imaging, computed tomography imaging, single-photon emission computed tomography imaging, and photothermal therapy of cancer.