Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy.

Wang, Jing; Liu, Jing; Liu, Ying; Wang, Liming; Cao, Mingjing; Ji, Yinglu; Wu, Xiaochun; Xu, Yingying et al. · Adv Mater · 2016

basic_science · Level V

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Abstract

An original gadolinium-hybridized plasmonic gold nanocomposite is fabricated to provide an insightful and attractive strategy to overcome both the physiological and pathological barriers of tumor, and increase the transportation and permeability of imaging agents and drugs in tumor interior for achieving high-sensitive multimodal imaging and simultaneously improving the therapeutic efficacy of cancer.

Medical subject headings