The Whole (Cell) Is Less Than the Sum of Its Parts.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27565337.
- Also identified by DOI 10.1016/j.cell.2016.08.011 and PMC identifier 5260058.
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Abstract
Despite advances in metabolite profiling, a full picture of the metabolic landscape of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient pools into membrane-bound organelles. Now, Chen et al. describe methods for overcoming this hurdle and provide a new quantitative picture of the mitochondrial metabolome.
Medical subject headings
- Metabolome
- Organelles