Surface Acoustic Waves Grant Superior Spatial Control of Cells Embedded in Hydrogel Fibers.

Lata, James P; Guo, Feng; Guo, Jinshan; Huang, Po-Hsun; Yang, Jian; Huang, Tony Jun · Adv Mater · 2016

basic_science · Level V

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Abstract

By exploiting surface acoustic waves and a coupling layer technique, cells are patterned within a photosensitive hydrogel fiber to mimic physiological cell arrangement in tissues. The aligned cell-polymer matrix is polymerized with short exposure to UV light and the fiber is extracted. These patterned cell fibers are manipulated into simple and complex architectures, demonstrating feasibility for tissue-engineering applications.