Nanoscale Polymer Metal-Organic Framework Hybrids for Effective Photothermal Therapy of Colon Cancers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27573036.
- Also identified by DOI 10.1002/adma.201602997.
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Abstract
A UiO-66 core with various sizes acts as heterogeneous nucleation center and enables aniline polymerization under ambient conditions. The as-synthesized UiO-66@PAN possesses uniform size and excellent dispersibility in aqueous solution. UiO-66@PAN can be internalized by cancer cells via endocytosis, and indicates significant photothermal therapeutic effect in vitro, and can effectively inhibit the growth of colon cancers in vivo.
Medical subject headings
- Colonic Neoplasms
- Hyperthermia, Induced
- Metal-Organic Frameworks
- Phototherapy
- Polymers