Intraductal Oncocytic Papillary Neoplasms of the Pancreas.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27575268.
- Also identified by DOI 10.5858/arpa.2014-0595-RS.
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Abstract
Intraductal oncocytic papillary neoplasms (IOPNs) are cystic neoplasms with intraductal growth and complex papillae composed of oncocytic cells. IOPNs have been reported both in the pancreas and biliary tree, and are most likely closely related in these 2 locations. In the pancreas, these rare tumors are now considered 1 of the 4 histologic subtypes of intraductal papillary mucinous neoplasm (IPMN). Significant differences in histology, immunophenotype, and molecular genetics have been reported between IOPNs and other IPMN subtypes. However, there are limited data regarding the clinical behavior and prognosis of IOPNs in comparison to other subtypes of IPMN. We review features of pancreatic IOPNs and discuss the differential diagnosis of other intraductal lesions in the pancreas.
Medical subject headings
- Adenoma, Oxyphilic
- Carcinoma, Pancreatic Ductal
- Carcinoma, Papillary
- Pancreas
- Pancreatic Neoplasms