Stem Cell Fate Is a Touchy Subject.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27588745.
- Also identified by DOI 10.1016/j.stem.2016.08.015.
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Abstract
Uncoupling synergistic interactions between physio-chemical cues that guide stem cell fate may improve efforts to direct their differentiation in culture. Using supramolecular hydrogels, Alakpa et al. (2016) demonstrate that mesenchymal stem cell differentiation is paired to depletion of bioactive metabolites, which can be utilized to chemically induce osteoblast and chondrocyte fate.
Medical subject headings
- Cell Differentiation
- Mesenchymal Stem Cells