DAPAR & ProStaR: software to perform statistical analyses in quantitative discovery proteomics.
Where this comes from
- Record sourced from PubMed, PMID 27605098.
- Also identified by DOI 10.1093/bioinformatics/btw580 and PMC identifier 5408771.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
DAPAR and ProStaR are software tools to perform the statistical analysis of label-free XIC-based quantitative discovery proteomics experiments. DAPAR contains procedures to filter, normalize, impute missing value, aggregate peptide intensities, perform null hypothesis significance tests and select the most likely differentially abundant proteins with a corresponding false discovery rate. ProStaR is a graphical user interface that allows friendly access to the DAPAR functionalities through a web browser. DAPAR and ProStaR are implemented in the R language and are available on the website of the Bioconductor project (http://www.bioconductor.org/). A complete tutorial and a toy dataset are accompanying the packages. samuel.wieczorek@cea.fr, florence.combes@cea.fr, thomas.burger@cea.fr.
Medical subject headings
- Peptides
- Proteins
- Proteomics
- Software