Teaching a Clone to Walk, One Step at a Time.

Crowe, James E · Cell · 2016

editorial · Level V

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Abstract

Development of broad HIV neutralizing antibodies during infection requires prolonged exposure to viral variants. A series of three studies published in this issue of Cell and a related paper in Immunity report new HIV structure-based design efforts focused on sequential boosting regimens with antigens of increasing maturation that point the way forward for an effective HIV vaccine strategy.

Medical subject headings