Gating Immunity and Death at the Nuclear Pore Complex.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27610561.
- Also identified by DOI 10.1016/j.cell.2016.08.026 and PMC identifier 6310161.
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Abstract
The nuclear pore complex is the primary conduit for nuclear import and export of molecules. In this issue, Gu et al. uncover a novel mechanism in which immune signaling and programmed cell death require nuclear pore rearrangement and release of sequestered cyclin-dependent kinase inhibitors to elicit immunity and death.
Medical subject headings
- Active Transport, Cell Nucleus
- Nuclear Pore