The Irony of Tumor-Induced Inflammation.

Greten, Florian R · Cell Metab · 2016

editorial · Level V

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Abstract

Increased dietary iron intake and elevated systemic iron levels are associated with increased cancer risk. In this issue, Xue et al. (2016) have identified an unexpected link between intracellular iron accumulation and pro-inflammatory signaling that provides, at least in part, a molecular explanation for the tumor-promoting effects of iron.

Medical subject headings