Mitochondrial Transfer from Astrocytes to Neurons following Ischemic Insult: Guilt by Association?

Berridge, Michael V; Schneider, Remy T; McConnell, Melanie J · Cell Metab · 2016

editorial · Level V

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Abstract

Intercellular mitochondrial transfer has been shown in tumor models, following lung injury and in xenotransplants of leukemic cells, but trafficking between cells in the brain remains unexplored. A suggestion that mitochondria move from astrocytes to neurons in a model of ischemia in a recent article in Nature by Hayakawa et al. (2016) should be interpreted with caution.

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