Diving into the abyss of undiscovered kidney function-related factors.

Limou, Sophie; Parsa, Afshin · Kidney Int · 2016

other · Level V

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Abstract

Meta-analyses and reintroduction of biological knowledge are 2 classic strategies to increase genomewide association study statistical power and overcome the burden of multiple testing. These strategies have empowered the nephrology community to discover new signals associated with kidney function and nephropathies. Here we discuss the current genomewide association study limitations and strategies to dive further into the abyss of yet-to-be discovered kidney function-related factors.

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