Pulmonary Kirsten Rat Sarcoma Virus Mutation Positive Mucinous Adenocarcinoma Arising in a Congenital Pulmonary Airway Malformation, Mixed Type 1 and 2.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 27645976.
- Also identified by DOI 10.1016/j.athoracsur.2016.01.104.
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Abstract
Congenital pulmonary airway malformation (CPAM) is a developmental abnormality of the lung, which results from an abnormality of branching during fetal development of the lung. We report the case of an 18 year-old woman who developed Kirsten rat sarcoma virus (KRAS) mutation positive mucinous adenocarcinoma of the lung (AC) in association with mixed CPAM type 1 and 2. This case is unique as KRAS mutation positive AC is present in a setting of both CPAM 1 and 2 in the same lesion.
Medical subject headings
- Adenocarcinoma
- Cystic Adenomatoid Malformation of Lung, Congenital
- Kirsten murine sarcoma virus
- Lung Neoplasms
- Mutation
- Proto-Oncogene Proteins p21(ras)