Timeline: Targeted Treatment of Hepatitis C Virus.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27662096.
- Also identified by DOI 10.1016/j.cell.2016.08.066.
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Abstract
Chronic hepatitis C virus infection can cause liver cirrhosis and cancer, and early treatment options were non-specific and could be toxic. Work aimed at elucidating the viral life cycle has led to better treatment options through the development of direct-acting antivirals, as exemplified by the work of Ralf Bartenschlager, Charles Rice, and Michael Sofia who have received the Lasker∼DeBakey Clinical Medical Research Award for their work on this effort. Key events in understanding HCV replication and development of direct-acting antivirals are shown in this Timeline.