Bringing Blood-Based Molecular Testing to the Clinic.

Janku, Filip; Kurzrock, Razelle · Clin Cancer Res · 2016

review · Level V

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Abstract

In cancer, plasma-derived cell-free DNA can be used for detection of oncogenic aberrations relevant for treatment selection. A cell-free DNA-based test for EGFR mutations has been approved as an alternative to tumor tissue analysis in lung cancer. Testing for other aberrations, including copy number alterations, continues to be investigated. Clin Cancer Res; 22(22); 5400-2. ©2016 AACRSee related article by Chicard et al., p. 5564.

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