Human milk oligosaccharides and development of cow's milk allergy in infants.

Seppo, Antti E; Autran, Chloe A; Bode, Lars; Järvinen, Kirsi M · J Allergy Clin Immunol · 2017

case_control · Level III

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Abstract

Human milk oligosaccharides (HMOs) provide a main substrate to help shape the infant's gut microbiota and affect the maturation of the intestinal mucosal immune system. In our cohort, infants that received human milk with low Lacto-N-fucopentaose (LNFP) III concentrations (< 60μM) were more likely to become affected with cow's milk allergy when compared to high LNFP III-containing milk (odds ratio 6.7, 95% CI 2.0-22).

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