Digit Tip Regeneration and Beyond: Schwann Cell Progenitors to the Rescue.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27716518.
- Also identified by DOI 10.1016/j.stem.2016.09.006.
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Abstract
Digit tip regeneration following amputation is an innate response in some mammals, including mice. In this issue of Cell Stem Cell, Johnston et al. (2016) show that Schwann cell precursors are necessary for this process and can rescue regeneration in denervated digit tips through secretion of pro-regenerative factors including OSM and PDGF-AA.
Medical subject headings
- Regeneration
- Stem Cells