Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27716520.
- Also identified by DOI 10.1016/j.stem.2016.09.009.
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Abstract
Mammalian skin is a complex and heterogeneous tissue with several distinct compartments and stem cell populations. Joost et al. (2016) now use single-cell RNaseq to comprehensively reconstruct this complexity, revealing spatial and pseudotemporal differences between transcriptional programs in distinct compartments and a common basal program in skin stem cell populations.
Medical subject headings
- Skin
- Stem Cells