Human ESC-Derived Interneurons Improve Major Consequences of Spinal Cord Injury.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27716521.
- Also identified by DOI 10.1016/j.stem.2016.09.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Beyond impaired motor and sensory function, neuropathic pain and loss of bladder control caused by spinal cord injuries (SCIs) can severely affect quality of life. In this issue of Cell Stem Cell, Fandel et al. (2016) show that transplanted human ESC-derived cells biased to produce inhibitory interneurons significantly improve pain and bladder function in rodent SCI models.
Medical subject headings
- Human Embryonic Stem Cells
- Interneurons
- Spinal Cord Injuries