Hypothesis Driven versus Hypothesis-free: Filling the Gaps in CoQ Biosynthesis.

Enríquez, José Antonio; Sánchez-Cabo, Fátima; Vázquez, Jesús · Cell Metab · 2016

editorial · Level V

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Abstract

Two independent investigations based on the power of yeast genetics, but using radically different discovery-driven approaches, have solved a long-pursued goal: the understanding of the early steps in CoQ biosynthesis, which may help diagnose CoQ deficiencies of unknown origin (Payet et al., 2016; Stefely et al., 2016).

Medical subject headings