A fluidic circuit based, high-efficiency and large-scale single cell trap.

Mi, Lu; Huang, Liang; Li, Junxiang; Xu, Guoqiang; Wu, Qiong; Wang, Wenhui · Lab Chip · 2016

basic_science · Level V

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Abstract

Single cell traps have important applications in biological cell manipulation and analysis. This paper describes a novel single cell trap design and device with a matrix of cell trap units inspired by an equivalent resistive electric circuit. This fluidic device follows the least flow resistance path principle of such devices allowing deterministic single cell trapping with high efficiency and flexibility for large scale cell patterning.

Medical subject headings