Journal Club: Exacerbation of headache during dihydroergotamine for chronic migraine does not alter outcome.

Woldeamanuel, Yohannes W; O'Hare, Meabh; DeSouza, Danielle D; Cowan, Robert P · Neurology · 2016

review · Level V

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Abstract

Transient headache exacerbation during IV dihydroergotamine (DHE) therapy of migraine may prompt clinicians to prematurely discontinue DHE therapy, potentially depriving patients of the full benefit of DHE infusion. In a recent Neurology® article, Eller et al. evaluated whether or not worsening headache during DHE infusion was associated with suboptimal medium-term headache outcomes.

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