Zika Virus: The Agent and Its Biology, With Relevance to Pathology.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27763795.
- Also identified by DOI 10.5858/arpa.2016-0409-RA.
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Abstract
Once obscure, Zika virus (ZIKV) has attracted significant medical and scientific attention in the past year because of large outbreaks associated with the recent introduction of this virus into the Western hemisphere. In particular, the occurrence of severe congenital infections and cases of Guillain-Barré syndrome has placed this virus squarely in the eyes of clinical and anatomic pathologists. This review article provides a basic introduction to ZIKV, its genetics, its structural characteristics, and its biology. A multidisciplinary effort will be essential to establish clinicopathologic correlations of the basic virology of ZIKV in order to advance development of diagnostics, therapeutics, and vaccines.
Medical subject headings
- Disease Outbreaks
- Zika Virus
- Zika Virus Infection