Glucagon and Thyroid Hormone: A Championship Team.

Saghatelian, Alan; Cravatt, Ben · Cell · 2016

basic_science · Level V

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Abstract

A bioactive peptide that combines glucagon with the thyroid hormone T3 lowers lipid levels, improves glucose tolerance, and promotes energy expenditure to treat symptoms and underlying causes of metabolic disease. The two active components both maximize their combined benefits and mitigate the negative consequences of treatment with each alone.

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