Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?

Ogburn, Ryenne N; Randall, Thomas A; Xu, Yingrong; Roberts, Julia H; Mebrahtu, Betelihem; Karnuta, Jaret M; Rider, S Dean; Kissling, Grace E et al. · J Allergy Clin Immunol · 2017

basic_science · Level V

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Abstract

RNA-seq and denaturation studies demonstrated that allergens are among the most highly expressed and stable proteins from <i>Dermatophagoides pteronyssinus</i>. The combination of high levels of transcription and stability for the major allergens Der p 1, Der p 2, and Der p 23 is rare.

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