CLIP Tool Kit (CTK): a flexible and robust pipeline to analyze CLIP sequencing data.

Shah, Ankeeta; Qian, Yingzhi; Weyn-Vanhentenryck, Sebastien M; Zhang, Chaolin · Bioinformatics · 2017

basic_science · Level V

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Abstract

UV cross-linking and immunoprecipitation (CLIP), followed by high-throughput sequencing, is a powerful biochemical assay that maps in vivo protein-RNA interactions on a genome-wide scale. The CLIP Tool Kit (CTK) aims at providing a set of tools for flexible, streamlined and comprehensive CLIP data analysis. This software package extends the scope of our original CIMS package. The software is implemented in Perl. The source code and detailed documentation are available at http://zhanglab.c2b2.columbia.edu/index.php/CTK . cz2294@columbia.edu.

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