Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27814473.
- Also identified by DOI 10.1016/j.stem.2016.10.012.
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Abstract
Mesenchymal stem/progenitor cells (MSPCs) have recently gained attention as key elements that contribute to different stages of oncogenesis, from predisposition to disease manifestation and evolution. In this issue of Cell Stem Cell, Zambetti et al. (2016) propose a mechanism by which mutated MSPCs transform hematopoietic cells into a malignant-prone state.
Medical subject headings
- Hematopoietic Stem Cells
- Mesenchymal Stem Cells