MIS12/MIND Control at the Kinetochore.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27814517.
- Also identified by DOI 10.1016/j.cell.2016.10.036.
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Abstract
Kinetochores are complex multiprotein machines that link chromosomes to dynamic microtubules for chromosome segregation. Two studies in Cell reveal the structure of the human MIS12 and budding yeast MIND kinetochore complexes and the regulatory mechanisms that enable them to link chromosomes to microtubules during mitosis.
Medical subject headings
- Chromosome Segregation
- Kinetochores