Can We Trust Knee Meniscus Studies? One-Way Crossover Confounds Intent-to-Treat Statistical Methods.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27816090.
- Also identified by DOI 10.1016/j.arthro.2016.09.009.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Randomized controlled studies have a high level of evidence. However, some patients are not treated in the manner to which they were randomized and actually switch to the alternative treatment (crossover). In such cases, "intent-to-treat" statistical methods require that such a switch be ignored, resulting in bias. Thus, the study conclusions could be wrong. This bias is a common problem in the knee meniscus literature.
Medical subject headings
- Data Interpretation, Statistical
- Intention to Treat Analysis
- Randomized Controlled Trials as Topic
- Research Design
Anatomy
- knee