Caspase-2 and tau-a toxic partnership?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27824824.
- Also identified by DOI 10.1038/nm.4227 and PMC identifier 9353876.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Misfolded and hyperphosphorylated forms of the microtubule-associated protein tau are thought to be responsible for some degree of neurodegeneration. The demonstration of a novel toxic cleavage of tau by caspase-2 opens up new therapeutic avenues.
Medical subject headings
- Caspase 2
- tau Proteins