Arginine Arms T Cells to Thrive and Survive.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27829132.
- Also identified by DOI 10.1016/j.cmet.2016.10.019 and PMC identifier 6327309.
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Abstract
A clear role for cellular metabolism in regulating immune cell function has recently been established. In a recent issue of Cell, Geiger et al. (2016) demonstrate a role for intracellular arginine abundance in T cells for the promotion of oxidative metabolism, increased cell viability, persistence, and in vivo antitumor response.
Medical subject headings
- Arginine
- T-Lymphocytes