Gal3 Links Inflammation and Insulin Resistance.

Siwicki, Marie; Engblom, Camilla; Pittet, Mikael J · Cell Metab · 2016

editorial · Level V

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Abstract

The connection between obesity-induced insulin resistance and inflammation is established, but targeting inflammatory mediators like TNF-α and IL-1β have had limited success improving insulin sensitivity in patients. Now, Li et al. (2016) indicate that galectin-3 could be a targetable link between inflammation and insulin sensitivity.

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