Serum β-hCG as an Indicator of Recurrence After the Complete Resection of a Malignant Solitary Fibrous Tumor of the Pleura.

Yabuki, Hiroshi; Sakurada, Akira; Niikawa, Hiromichi; Notsuda, Hirotsugu; Endo, Chiaki; Matsuda, Yasushi; Noda, Masafumi; Saito, Ryoko et al. · Ann Thorac Surg · 2016

case_report · Level V

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Abstract

In solitary fibrous tumors (SFTs) of the pleura, malignant SFTs are uncommon. Although SFTs are known to cause paraneoplastic syndromes through the production of insulin-like growth factor, to the best of our knowledge, the production of beta-human chorionic gonadotropin (β-hCG) has been reported only in 1 case involving a patient with a benign SFT. We herein report the first case of the elevation of β-hCG serum levels associated with a malignant SFT in which the β-hCG serum level became a useful indicator of recurrence after the complete resection of the primary mediastinal lesion.

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