DNA repair: Clamping down on copy errors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27851733.
- Also identified by DOI 10.1038/nature20475 and PMC identifier PMC3964087.
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Abstract
Repair enzymes must communicate across hundreds of nucleotides to undo errors made during DNA replication. Imaging reveals that the enzymes do this by forming a series of ring-like clamps that diffuse along the DNA.