A Powerful CD8<sup>+</sup> T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27859662.
- Also identified by DOI 10.1002/adma.201601776.
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Abstract
A novel vaccine adjuvant based on a supramolecular hydrogel of a D-tetra-peptide is reported. Antigens can be easily incorporated into the hydrogel by a vortex or by gently shaking before injection. The vaccines can stimulate strong CD8+ T-cell responses, which significantly inhibits tumor growth. This novel adjuvant is expected to enable a wide range of sub-unit vaccines and help the production of antibodies.
Medical subject headings
- CD8-Positive T-Lymphocytes