Core-Shell Gold Nanorod@Metal-Organic Framework Nanoprobes for Multimodality Diagnosis of Glioma.

Shang, Wenting; Zeng, Chaoting; Du, Yang; Hui, Hui; Liang, Xiao; Chi, Chongwei; Wang, Kun; Wang, Zhongliang et al. · Adv Mater · 2017

basic_science · Level V

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Abstract

One of the most significant challenges in the diagnosis of brain cancer is efficient in vivo imaging using nontoxic nanoprobes. Core-shell gold nanorod@MIL-88(Fe) nanostars are successfully constructed as triple-modality imaging (computed tomography/magnetic-resonance imaging/photoacoustic imaging) nanoprobes that show low cytotoxicity, high contrast, high penetration depth, and high spatial resolution for accurate and noninvasive imaging and diagnosis of gliomas.

Medical subject headings