Porphyrin-Based Carbon Dots for Photodynamic Therapy of Hepatoma.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27860468.
- Also identified by DOI 10.1002/adhm.201600924.
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Abstract
Porphyrin-containing carbon dots (CDs) possess ultrasmall size, excellent water solubility, and photostability. These CDs can effectively generate cytotoxic singlet oxygen upon irradiation, and induce the cell apoptosis. Photodynamic ability of CDs inhibits the growth of hepatoma. This work not only sheds light on developing functional carbon dots, but also highlights the importance of special-structure precursor molecules in synthesizing functional CDs.
Medical subject headings
- Carbon
- Carcinoma, Hepatocellular
- Liver Neoplasms
- Nanoparticles
- Photochemotherapy
- Porphyrins