Malformations of cortical development.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27862206.
- Also identified by DOI 10.1002/ana.24793 and PMC identifier 5177533.
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Abstract
Malformations of cortical development (MCDs) compose a diverse range of disorders that are common causes of neurodevelopmental delay and epilepsy. With improved imaging and genetic methodologies, the underlying molecular and pathobiological characteristics of several MCDs have been recently elucidated. In this review, we discuss genetic and molecular alterations that disrupt normal cortical development, with emphasis on recent discoveries, and provide detailed radiological features of the most common and important MCDs. Ann Neurol 2016;80:797-810.
Medical subject headings
- Malformations of Cortical Development